- Paul Reubens Character (Pee-wee Herman)
- E.G. Daily Character (Dottie)
- Mark Holton Character (Francis)
- Diane Salinger Character (Simone)
- Judd Omen Character (Mickey)
- Irving Hellman Character (Mr. Crowtrey)
- Bill Cable Character (Policeman #1)
- Peter Looney Character (Policeman #2)
- Starletta DuPois Character (Sgt. Hunter)
- Lou Cutell Character (Amazing Larry)
- Monte Landis Character (Mario)
- Milton Berle Character (Himself)
- Jan Hooks Character (Tina)
- James Brolin Character (Himself - as PeeWee)
- Morgan Fairchild Character (Herself - as 'Dottie')
- Dee Snider Character (Himself (as Twisted Sister))
- Simmy Bow Character (Man in Diner)
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